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High quality raw material Spiramycin Base CAS No.:8025-81-8 Pharmaceutical Grade
Product Description
Spiramycin is a macrolide antibiotic. It is used to treat toxoplasmosis and various other infections of soft tissues. Although used in Europe, Canada and Mexico, spiramycin is still considered an experimental drug in the United States, but can sometimes be obtained by special permission from the FDA for toxoplasmosis in the first trimester of pregnancy.
Parameters
Items
Specifications
Results
Appearance
A white or slightly yellowish powder
White powder
Identification
Conform
A. UV Spectrum
The specific absorbance at the maximum (232nm) is about 340.
B. TLC
Corresponds to reference solution.
C. Color Reaction
Brown colour.
pH
8.5-10.5
9.6
Specific optical rotation
-80°- -85°(dried substance)
-83°
Composition (HPLC)
SpiramycinⅠ≥80.0 %
88.20%
SpiramycinⅡ≤5.0 %
0.30%
SpiramycinⅢ≤10.0 %
3.70%
Total Spiramycins ≥90.0 %
92.20%
Related substances (HPLC)
≤2.0 %
Conform
Heavy metals
≤20ppm
Conform
Loss on drying
≤3.5 %
1.40%
Sulphated ash
≤0.1 %
Conform
Assay (wet substance)
No limits (IU/mg)
4305 IU/mg
Assay (dried substance)
≥4100 IU/mg
4366 IU/mg
CONCLUSION
CONFORM TO EP VII
Function
Spiramycin is applicable to the infections caused by sensitive bacteria of the following kinds:
2. Urinary tract infections: chlamydia infection and prostate infection, etc.
3. The orthopaedic: osteomyelitis, etc.
4. The parasitic infection toxoplasmosis, cryptosporidiosis.
5. Others: skin soft tissue infection
Application
This product can be used for the infections in ears, nasus, larynx and respiratory tract systemcaused by gram-positive bacterium and some gram-negative bacterium such as acute bronchitic, acute bout of acute bronchitis, pneumonia, scarlet fever, tonsillitis, tympanitis, periodontitis and acute nososinusitis. It also shows suitable to non-gonococcal urethritis. It possesses strong internal antibacterial function and Post-Antibiotic Effect (PAE). It’s able to improve the phagocytosis of phagocyte and is widely distributed in body. The concentration in histiocyte is higher than erythromycin and is less adverse reaction as well.
Packaging & Shipping
Packaging Detail
0.5kgs/Al-Bottle
1.0kgs/Al- Bottle
2.0kgs/Al- Bottle
5.0 kgs/Al-Bottle
25.0 kgs/drum
or upon customers' request.
Storage
Store in a well-closed container away from moisture
Shelf Life
2 years if sealed and store away from direct sun light.
Delivery Detail
within 3 days after get the payment
· Storage:Stored in dry and cool place, keep away from strong light and heat.